Emilie Moatti was born in 1980 and grew up in Netanya in a religious family of Tunisian origin. The oldest of six siblings, she dropped out of high school to go to work. In 2003, she traveled to Paris to study at the Sorbonne. She also worked in Paris as a producer and spokesperson for the Israeli Cinema Festival, and joined a number of forums dealing with Jewish cultural matters. She was involved in two left-wing peace projects: the Geneva Initiative and the Israel Regional Initiative. Since 2014, she has been a member of the board of WePower, a feminist NGO whose goal is to integrate women into the municipal and national political spectrum. She was a candidate for the Labor Party in the 2020 parliamentary elections.
Moatti is a publicist, politician, and a social activist who appears regularly as a commentator on various Israeli TV channels. She was awarded the Education Ministry Prize for First Book in 2018 for her novel Blue Marks, film rights of which have been sold.